Top 100 Gene ranking

RankAccessIdGeneDefinition
1385nfa35380roxrifampin monooxygenase (low-level rifampin resistance _RESISTANCE; rifampin decoloration)
2218nfa53110cytochrome P450 monooxygenase (CYP154; F92A mutation results in altered regioselectivity (Bracco et al. PMID:24134652, PMID:25372679, PMID:33145893))
3180nfa15250hypothetical protein (_PHAGE; putative intein at position 1682370..1683308 (found by Prof. S. Pietrokovski))
4177nfa45140oxidoreductase (antigenic protein PMID:31487535)
5176nfa55680hypothetical protein (tellurium resistance protein? antigenic protein PMID:31487535)
6167nfa55760dnaBreplicative DNA helicase (putative intein at position 5911033..5912307 (found by Prof. S. Pietrokovski))
7161nfa43070nrdEribonucleoside-diphosphate reductase alpha subunit (putative intein at position 4465995..4467221 (found by Prof. S. Pietrokovski))
8136nfa48660hypothetical protein (tellurium resistance protein? antigenic protein PMID:31487535)
9136nfa15900nfpBcell wall channel protein (forms hetero-oligomer with NfpA; antigenic protein PMID:31487535)
10135nfa49580hypothetical protein (adhesin like? antigenic protein PMID:31487535)
1127nfa9460sdhBsuccinate dehydrogenase iron-sulfur subunit
1227nfa9420hypothetical protein
1327nfa9470sdhAsuccinate dehydrogenase flavoprotein subunit
1427nfa9450hypothetical protein
1526nfa54930hypothetical protein (transporter membrane protein?)
1626nfa9440hypothetical protein
1726nfa9430radCDNA repair protein
1825nfa14510transcriptional regulator (TetR)
1925nfa11870transcriptional regulator (TetR)
2024nfa46320hypothetical protein
2124nfa44370transposase (frameshift)
2214nfa1810fbpAmycolyltransferase (Ag85 family; fibronectin-binding protein; secreted; _VIRULENCE)
239nfa1210sodFsuperoxide dismutase (iron/manganese; F means Fe; _VIRULENCE)
247nfa7630nbtAthioesterase (nocobactin; type II thioesterase; also like MbtB; upstream IdeR box-like sequence; _VIRULENCE)
257nfa6160glycosyltransferase (lipoarabinomannan; polyprenol phosphate mannosyltransferase? _VIRULENCE)
266nfa7940secYpreprotein translocase subunit
276nfa7610nbtGlysine-N-oxygenase (nocobactin; MbtG ortholog; upstream IdeR box-like sequence; _VIRULENCE)
286nfa17990hypothetical protein
296nfa52470carbohydrate kinase
306nfa7950adkadenylate kinase
316nfa46090lipoprotein
326nfa30260esterase (mycolyltransferase? Ag85 family; _VIRULENCE)
336nfa7660nbtDnon-ribosomal peptide synthetase (nocobactin; MbtE ortholog; _VIRULENCE)
346nfa52520ATP-dependent DNA ligase
356nfa8400heat shock protein (hspX homolog; alpha-crystallin family; 16kDa antigen)
366nfa7640nbtBpolyketide synthase (nocobactin; MbtC ortholog; _VIRULENCE)
376nfa8270membrane protein (homologous (45%) to the Rv3877, which located in the RD1 region of Mtub.; type VII secretion integral membrane protein EccD homolog)
386nfa7670nbtEnon-ribosomal peptide synthetase (nocobactin; lysine; MbtF ortholog; e-caprolactam formation; _VIRULENCE)
396nfa42470two-component system sensor kinase
406nfa8960hypothetical protein
416nfa8800hydrolase
426nfa1840esterase (Ag85 family; mycolyltransferase? C. glutamicum PS1 homolog; larger than mtub Ag85; _VIRULENCE)
436nfa7920rpmDribosomal protein L30
446nfa8420hypothetical protein
456nfa8790alralanine racemase
466nfa7930rplOribosomal protein L15
476nfa8840glycoprotease (O-sialoglycoprotein endopeptidase)
486nfa7620nbtHlysine-N-acetyltransferase (nocobactin; aerobactin biosynthesis protein homolog; upstream IdeR box-like sequence; _VIRULENCE)
496nfa8240hypothetical protein (type VII secretion protein EccE homolog)
506nfa52080heparin-binding hemagglutinin (adhesin; _VIRULENCE; not found in M. smegmatis; may play a role in extrapulmonary dissemination)
515nfa54910two-component system response regulator
525nfa8820hypothetical protein
535nfa8480ion transporter
545nfa11200mce2FMce family protein (_VIRULENCE)
555nfa54440echA22enoyl-CoA hydratase/isomerase family protein
565nfa3220branched-chain amino acid aminotransferase
575nfa54170protease
585nfa56580hypothetical protein
595nfa37970hrpAATP-dependent helicase
605nfa11040hypothetical protein (low homology to non-ribosomal peptide synthetases)
615nfa39870hypothetical protein (_PHAGE)
625nfa47970xseAexodeoxyribonuclease VII large subunit
635nfa54640transcriptional regulator (TetR)
645nfa38250fadE35acyl-CoA dehydrogenase
655nfa54980hypothetical protein
665nfa5640hypothetical protein
675nfa56570hypothetical protein
685nfa52650dihydrolipoamide dehydrogenase (_TCA)
695nfa42310ilvNacetolactate synthase small subunit
705nfa4560ATPase
715nfa6610citrate synthase (_TCA)
725nfa39940hypothetical protein (_PHAGE)
735nfa41320hypothetical protein
745nfa50400hypothetical protein
755nfa2900hypothetical protein (polyketide cyclase/dehydrase domain)
765nfa40430DNA polymerase (exonuclease? _PHAGE)
775nfa53120hypothetical protein (OsmC-like protein)
785nfa31540cobKprecorrin 6X reductase
795nfa52740hypothetical protein
805nfa51900sugar kinase
815nfa6150hypothetical protein
825nfa7110phage integrase (_PHAGE)
835nfa7310hypothetical protein
845nfa400hypothetical protein (_PHAGE)
855nfa39630hypothetical protein (_PHAGE)
865nfa11980hypothetical protein
875nfa8620hypothetical protein
885nfa6960hydrolase
895nfa5660hypothetical protein
905nfa54220fadE47acyl-CoA dehydrogenase
915nfa13810thrS2threonyl-tRNA synthetase
925nfa55010transcriptional regulator
935nfa21520transcriptional regulator
945nfa52620hypothetical protein
955nfa3980ftsHcell division protein (protease)
965nfa21790hypothetical protein
975nfa39780hypothetical protein (_PHAGE)
985nfa40970monooxygenase (steroid?)
995nfa54350hypothetical protein
1005nfa9600phosphomannomutase