Top 100 Gene ranking

RankAccessIdGeneDefinition
11948nfa35380roxrifampin monooxygenase (low-level rifampin resistance _RESISTANCE; rifampin decoloration)
2216nfa15900nfpBcell wall channel protein (forms hetero-oligomer with NfpA; antigenic protein PMID:31487535)
3207nfa55760dnaBreplicative DNA helicase (putative intein at position 5911033..5912307 (found by Prof. S. Pietrokovski))
4196nfa34100acyl dehydratase (ortholog of Rv0130, which has 3-hydroxyacyl-thioester dehydratase activity. PMID:18375556)
5195nfa48660hypothetical protein (tellurium resistance protein? antigenic protein PMID:31487535)
6187nfa53110cytochrome P450 monooxygenase (CYP154; F92A mutation results in altered regioselectivity (Bracco et al. PMID:24134652, PMID:25372679, PMID:33145893))
7177nfa49580hypothetical protein (adhesin like? antigenic protein PMID:31487535)
8171nfa52670dehydrogenase
9169nfa4150Clp protease
10168nfa23120hypothetical protein
11167nfa3860penicillin binding protein (D-alanyl-D-alanine carboxypeptidase)
12165nfa53150hypothetical protein
13165nfa8700ABC transporter ATP-binding protein
14163nfa15250hypothetical protein (_PHAGE; putative intein at position 1682370..1683308 (found by Prof. S. Pietrokovski))
15163nfa21360methyltransferase
16161nfa47090malate dehydrogenase
17160nfa36430hypothetical protein
18158nfa42870hypothetical protein
19157nfa8810hypothetical protein
20157nfa5990mshDmycothiol synthase (_MYCOTHIOL; GNAT; acetyl-CoA:1D-myo-inosityl 2-(L-cysteinyl)amido-2-deoxy-alpha-D-glucopyranoside acetyltransferase)
21157nfa29110hypothetical protein
22156nfa52270hypothetical protein
23156nfa44850ftsEcell division ABC transporter ATP-binding protein
24154nfa6210short chain dehydrogenase
25153nfa18590hypothetical protein
26152nfa34300folDmethylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
27152nfa10210branched-chain alpha-keto acid dehydrogenase component
28152nfa7720ferric nocobactin-binding protein (nocobactin; upstream IdeR box-like sequence; _VIRULENCE)
29152nfa4390tRNA/rRNA methyltransferase
30152nfa19730hypothetical protein (fosfomycin-modifying glutathione transferase?)
31149nfa52820fabH3-oxoacyl-ACP synthase (typeII fatty acid synthase system)
32149nfa23670hypothetical protein
33144nfa45270hypothetical protein
34144nfa14901-acylglycerol-3-phosphate O-acyltransferase
35143nfa860hypothetical protein
36143nfa44020transcriptional regulator
37142nfa104003-hydroxyisobutyrate dehydrogenase
38141nfa5310fadE9acyl-CoA dehydrogenase
39141nfa36440alaSalanyl-tRNA synthetase
40141nfa43930transcriptional regulator (AraC)
41140nfa47390hypothetical protein (lysine decarboxylase?)
42140nfa11590transcriptional regulator (MerR)
43140nfa24820hypothetical protein
44140nfa24890transcriptional regulator
45139nfa40730proSprolyl-tRNA synthetase
46139nfa5470trehalose-6-phosphate synthase
47139nfa45870hypothetical protein
48139nfa8240hypothetical protein (type VII secretion protein EccE homolog)
49138nfa25690hypothetical protein
50137nfa32890hypothetical protein
51137nfa43110transcriptional regulator (TetR)
52137nfa51470menA1,4-dihydroxy-2-naphthoate octaprenyltransferase (menaquinone/ubiquinone)
53137nfa17320aroG23-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase II (2-dehydro-3-deoxyphosphoheptonate aldolase)
54137nfa2310endoribonuclease (translation initiation inhibitor; Ininhibits protein synthesis by cleavage of mRNA)
55136nfa270hypothetical protein (_PHAGE)
56136nfa24030transcriptional regulator (TetR)
57136nfa16150fabDmalonyl-CoA-ACP acyltransferase (malonyl-CoA:ACP malonyltransferase; type II fatty acid synthase system)
58136nfa32980transcriptional regulator (TetR)
59136nfa25390ureFurease accessory protein
60135nfa38370glutamate transporter glutamate-binding protein
61135nfa45140oxidoreductase (antigenic protein PMID:31487535)
62135nfa42200leuBisopropylmalate dehydrogenase
63134nfa9890acyl-CoA carboxylase alpha subunit (biotin carboxylase subunit?)
64134nfa35560hypothetical protein (NifU-like)
65133nfa37120thrSthreonyl-tRNA synthetase
66133nfa11750gnd6-phosphogluconate dehydrogenase
67133nfa6030pstBphosphate transporter ATP-binding protein
68133nfa9310exonuclease
69133nfa49640two-component system response regulator
70132nfa56390hypothetical protein (ErfK/YbiS/YcfS/YnhG family)
71132nfa51800hypothetical protein
72132nfa21990short chain dehydrogenase
73131nfa24870transcriptional regulator
74131nfa55680hypothetical protein (tellurium resistance protein? antigenic protein PMID:31487535)
75130nfa12640hypothetical protein (alkyl hydroperoxide reductase or thiol-specific antioxidant protein)
76130nfa3250ferric uptake regulator (FurA homolog)
77130nfa44740transcriptional regulator
78130nfa18700two-component system response regulator
79130nfa37440rlmDribosomal RNA large subunit methyltransferase (U1939)
80130nfa16240hypothetical protein
81129nfa53840hypothetical protein
82128nfa51500hypothetical protein
83128nfa51030mce5EMce family protein (_VIRULENCE)
84127nfa6060dihydrouridine synthase
85126nfa28530ptsHphosphocarrier protein (PTS HPr component)
86126nfa55000hypothetical protein
87126nfa43070nrdEribonucleoside-diphosphate reductase alpha subunit (putative intein at position 4465995..4467221 (found by Prof. S. Pietrokovski))
88126nfa52650dihydrolipoamide dehydrogenase (_TCA)
89126nfa53370thiGthiamin-thiazole moiety synthesis
90125nfa41270cdsAphosphatidate cytidylyltransferase
91125nfa44700transcriptional regulator
92125nfa4370mecs2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (_NON-MEVALONATE; _MEP)
93125nfa24040short chain dehydrogenase
94125nfa34090phosphotransferase
95125nfa45700hypothetical protein
96124nfa27350phosphoglycerate mutase
97124nfa4480fadE2acyl-CoA dehydrogenase
98124nfa15880hypothetical protein (transcriptional regulator?)
99123nfa26690hypothetical protein
100123nfa42800glucose 6-O-methyltransferase (PMID:17640872)