Top 100 Gene ranking

RankAccessIdGeneDefinition
169nfa35380roxrifampin monooxygenase (low-level rifampin resistance _RESISTANCE; rifampin decoloration)
243nfa10dnaAreplication initiator protein
333nfa15900nfpBcell wall channel protein (forms hetero-oligomer with NfpA; antigenic protein PMID:31487535)
433nfa15250hypothetical protein (_PHAGE; putative intein at position 1682370..1683308 (found by Prof. S. Pietrokovski))
531nfa55760dnaBreplicative DNA helicase (putative intein at position 5911033..5912307 (found by Prof. S. Pietrokovski))
626nfa45140oxidoreductase (antigenic protein PMID:31487535)
725nfa53110cytochrome P450 monooxygenase (CYP154; F92A mutation results in altered regioselectivity (Bracco et al. PMID:24134652, PMID:25372679, PMID:33145893); Bioconversion of steroids (Yang et al. PMID:41756023))
821nfa55680hypothetical protein (tellurium resistance protein? antigenic protein PMID:31487535)
920nfa49580hypothetical protein (adhesin like? antigenic protein PMID:31487535)
1019nfa48660hypothetical protein (tellurium resistance protein? antigenic protein PMID:31487535)
1118nfa36440alaSalanyl-tRNA synthetase
1217nfa27350phosphoglycerate mutase
1317nfa51470menA1,4-dihydroxy-2-naphthoate octaprenyltransferase (menaquinone/ubiquinone)
1416nfa9930hypothetical protein
1516nfa5470trehalose-6-phosphate synthase
1616nfa16800hypothetical protein
1716nfa4150Clp protease
1816nfa29110hypothetical protein
1916nfa5310fadE9acyl-CoA dehydrogenase
2016nfa51800hypothetical protein
2116nfa6030pstBphosphate transporter ATP-binding protein
2216nfa4370mecs2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (_NON-MEVALONATE; _MEP)
2316nfa5990mshDmycothiol synthase (_MYCOTHIOL; GNAT; acetyl-CoA:1D-myo-inosityl 2-(L-cysteinyl)amido-2-deoxy-alpha-D-glucopyranoside acetyltransferase)
2416nfa30210acetyltransferase (GNAT)
2516nfa23670hypothetical protein
2615nfa1950aftAarabinofuranosyltransferase (arabinogalactan; AftA (Rv3792) ortholog; PMID:16595677)
2715nfa34900crtL2lycopene cyclase (lycopene beta-cyclase; generates beta- and/or gamma-carotene)
2815nfa6460transcriptional regulator (TetR)
2915nfa36230pyrBaspartate carbamoyltransferase
3015nfa52820fabH3-oxoacyl-ACP synthase (typeII fatty acid synthase system)
3115nfa8240hypothetical protein (type VII secretion protein EccE homolog)
3215nfa41270cdsAphosphatidate cytidylyltransferase
3315nfa36430hypothetical protein
3415nfa53370thiGthiamin-thiazole moiety synthesis
3514nfa13110DNA-binding protein
3614nfa44700transcriptional regulator
3714nfa3860penicillin binding protein (D-alanyl-D-alanine carboxypeptidase)
3814nfa22050fatty acid desaturase (_TERPENE)
3914nfa40100hypothetical protein (_PHAGE)
4014nfa52670dehydrogenase
4114nfa8810hypothetical protein
4214nfa270hypothetical protein (_PHAGE)
4314nfa9310exonuclease
4414nfa35560hypothetical protein (NifU-like)
4514nfa24820hypothetical protein
4614nfa51030mce5EMce family protein (_VIRULENCE)
4714nfa18420arylamine N-acetyltransferase (acetylate isoniazid (M. Martins et al. PMID:18778714))
4814nfa42800glucose 6-O-methyltransferase (PMID:17640872)
4914nfa17320aroG23-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase II (2-dehydro-3-deoxyphosphoheptonate aldolase)
5013nfa53020acetyltransferase (GNAT)
5113nfa28530ptsHphosphocarrier protein (PTS HPr component)
5213nfa41430hypothetical protein
5313nfa24910transcriptional regulator (TetR)
5413nfa7370rpsSribosomal protein S19
5513nfa56390hypothetical protein (ErfK/YbiS/YcfS/YnhG family)
5613nfa45700hypothetical protein
5713nfa34100acyl dehydratase (ortholog of Rv0130, which has 3-hydroxyacyl-thioester dehydratase activity. PMID:18375556)
5813nfa11750gnd6-phosphogluconate dehydrogenase
5913nfa45870hypothetical protein
6013nfa43070nrdEribonucleoside-diphosphate reductase alpha subunit (putative intein at position 4465995..4467221 (found by Prof. S. Pietrokovski))
6113nfa2940hypothetical protein
6213nfa18590hypothetical protein
6313nfa4120LSR2 protein (_VIRULENCE)
6413nfa10380fadE13acyl-CoA dehydrogenase
6513nfa350405-dehydro-4-deoxyglucarate dehydratase (dihydrodipicolinate synthase?)
6613nfa25690hypothetical protein
6713nfa41920hypothetical protein (epoxide hydrolase?)
6813nfa18940hypothetical protein
6913nfa104003-hydroxyisobutyrate dehydrogenase
7013nfa16240hypothetical protein
7113nfa41860hypothetical protein
7213nfa53840hypothetical protein
7313nfa23120hypothetical protein
7413nfa1800aftBterminal arabinosyltransferase (PMID:17387176)
7512nfa24490transcriptional regulator
7612nfa24870transcriptional regulator
7712nfa20790hypothetical protein
7812nfa34300folDmethylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
7912nfa5820hypothetical protein
8012nfa52620hypothetical protein
8112nfa2000oxidoreductase
8212nfa2300hypothetical protein
8312nfa47950lytBisoprenoid biosynthesis protein (_NON-MEVALONATE; _MEP; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase)
8412nfa16810hypothetical protein
8512nfa37440rlmDribosomal RNA large subunit methyltransferase (U1939)
8612nfa1940hypothetical protein
8712nfa53150hypothetical protein
8812nfa43980crtB2phytoene synthase (GGPP + IPP; 49 0dentity to Nfa17350)
8912nfa7570transporter
9012nfa11590transcriptional regulator (MerR)
9112nfa18700two-component system response regulator
9212nfa13690hypothetical protein
9311nfa5610esterase (mycolyltransferase? Ag85 family; secreted; _VIRULENCE)
9411nfa14030hypothetical protein
9511nfa51500hypothetical protein
9611nfa21000peptidase (glutamate carboxypeptidase?)
9711nfa38370glutamate transporter glutamate-binding protein
9811nfa16440hypothetical protein
9911nfa30860hypothetical protein (polyketide cyclase/dehydrase domain)
10011nfa21050oxidoreductase