Top 100 Gene ranking

RankAccessIdGeneDefinition
162nfa35380roxrifampin monooxygenase (low-level rifampin resistance _RESISTANCE; rifampin decoloration)
242nfa10dnaAreplication initiator protein
327nfa55760dnaBreplicative DNA helicase (putative intein at position 5911033..5912307 (found by Prof. S. Pietrokovski))
427nfa15250hypothetical protein (_PHAGE; putative intein at position 1682370..1683308 (found by Prof. S. Pietrokovski))
523nfa45140oxidoreductase (antigenic protein PMID:31487535)
621nfa53110cytochrome P450 monooxygenase (CYP154; F92A mutation results in altered regioselectivity (Bracco et al. PMID:24134652, PMID:25372679, PMID:33145893); Bioconversion of steroids (Yang et al. PMID:41756023))
720nfa15900nfpBcell wall channel protein (forms hetero-oligomer with NfpA; antigenic protein PMID:31487535)
818nfa49580hypothetical protein (adhesin like? antigenic protein PMID:31487535)
918nfa55680hypothetical protein (tellurium resistance protein? antigenic protein PMID:31487535)
1015nfa48660hypothetical protein (tellurium resistance protein? antigenic protein PMID:31487535)
1114nfa6460transcriptional regulator (TetR)
1214nfa36440alaSalanyl-tRNA synthetase
1314nfa16800hypothetical protein
1414nfa9930hypothetical protein
1513nfa34900crtL2lycopene cyclase (lycopene beta-cyclase; generates beta- and/or gamma-carotene)
1613nfa5310fadE9acyl-CoA dehydrogenase
1713nfa30210acetyltransferase (GNAT)
1813nfa4370mecs2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (_NON-MEVALONATE; _MEP)
1913nfa5470trehalose-6-phosphate synthase
2013nfa29110hypothetical protein
2113nfa8240hypothetical protein (type VII secretion protein EccE homolog)
2213nfa36230pyrBaspartate carbamoyltransferase
2313nfa23670hypothetical protein
2413nfa22050fatty acid desaturase (_TERPENE)
2513nfa27350phosphoglycerate mutase
2612nfa7370rpsSribosomal protein S19
2712nfa52820fabH3-oxoacyl-ACP synthase (typeII fatty acid synthase system)
2812nfa4120LSR2 protein (_VIRULENCE)
2912nfa9310exonuclease
3012nfa270hypothetical protein (_PHAGE)
3112nfa24820hypothetical protein
3212nfa53370thiGthiamin-thiazole moiety synthesis
3312nfa1950aftAarabinofuranosyltransferase (arabinogalactan; AftA (Rv3792) ortholog; PMID:16595677)
3412nfa51030mce5EMce family protein (_VIRULENCE)
3512nfa36430hypothetical protein
3612nfa5990mshDmycothiol synthase (_MYCOTHIOL; GNAT; acetyl-CoA:1D-myo-inosityl 2-(L-cysteinyl)amido-2-deoxy-alpha-D-glucopyranoside acetyltransferase)
3712nfa42800glucose 6-O-methyltransferase (PMID:17640872)
3811nfa18590hypothetical protein
3911nfa28530ptsHphosphocarrier protein (PTS HPr component)
4011nfa45700hypothetical protein
4111nfa20790hypothetical protein
4211nfa13690hypothetical protein
4311nfa34100acyl dehydratase (ortholog of Rv0130, which has 3-hydroxyacyl-thioester dehydratase activity. PMID:18375556)
4411nfa350405-dehydro-4-deoxyglucarate dehydratase (dihydrodipicolinate synthase?)
4511nfa18940hypothetical protein
4611nfa52670dehydrogenase
4711nfa6030pstBphosphate transporter ATP-binding protein
4811nfa16810hypothetical protein
4911nfa41430hypothetical protein
5011nfa2000oxidoreductase
5111nfa24910transcriptional regulator (TetR)
5211nfa13110DNA-binding protein
5311nfa16240hypothetical protein
5411nfa23120hypothetical protein
5511nfa56390hypothetical protein (ErfK/YbiS/YcfS/YnhG family)
5611nfa10380fadE13acyl-CoA dehydrogenase
5711nfa41860hypothetical protein
5811nfa51470menA1,4-dihydroxy-2-naphthoate octaprenyltransferase (menaquinone/ubiquinone)
5911nfa41920hypothetical protein (epoxide hydrolase?)
6011nfa35560hypothetical protein (NifU-like)
6111nfa4150Clp protease
6211nfa11750gnd6-phosphogluconate dehydrogenase
6311nfa45870hypothetical protein
6411nfa44700transcriptional regulator
6511nfa17320aroG23-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase II (2-dehydro-3-deoxyphosphoheptonate aldolase)
6611nfa3860penicillin binding protein (D-alanyl-D-alanine carboxypeptidase)
6711nfa41270cdsAphosphatidate cytidylyltransferase
6811nfa40100hypothetical protein (_PHAGE)
6911nfa8810hypothetical protein
7010nfa16440hypothetical protein
7110nfa43990crtI2phytoene desaturase (phytoene dehydrogenase; generates lycopene; 51 0dentity to Nfa17370)
7210nfa24870transcriptional regulator
7310nfa26380transcriptional regulator (TetR)
7410nfa2300hypothetical protein
7510nfa53340hypothetical protein
7610nfa34300folDmethylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
7710nfa1940hypothetical protein
7810nfa21000peptidase (glutamate carboxypeptidase?)
7910nfa1800aftBterminal arabinosyltransferase (PMID:17387176)
8010nfa2090hypothetical protein
8110nfa30820transporter permease
8210nfa2940hypothetical protein
8310nfa53020acetyltransferase (GNAT)
8410nfa43980crtB2phytoene synthase (GGPP + IPP; 49 0dentity to Nfa17350)
8510nfa24490transcriptional regulator
8610nfa18700two-component system response regulator
8710nfa7420rpsQribosomal protein S17
8810nfa23430hypothetical protein
8910nfa11590transcriptional regulator (MerR)
9010nfa22310glycosyltransferase
9110nfa5820hypothetical protein
9210nfa37440rlmDribosomal RNA large subunit methyltransferase (U1939)
9310nfa47950lytBisoprenoid biosynthesis protein (_NON-MEVALONATE; _MEP; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase)
9410nfa15620hypothetical protein (ESAT-6 homolog; type VII secretion target homolog)
9510nfa25690hypothetical protein
9610nfa7570transporter
9710nfa5610esterase (mycolyltransferase? Ag85 family; secreted; _VIRULENCE)
9810nfa19550ABC transporter membrane protein
999nfa2310endoribonuclease (translation initiation inhibitor; Ininhibits protein synthesis by cleavage of mRNA)
1009nfa14901-acylglycerol-3-phosphate O-acyltransferase