Top 100 Gene ranking

RankAccessIdGeneDefinition
11854nfa35380roxrifampin monooxygenase (low-level rifampin resistance _RESISTANCE; rifampin decoloration)
2187nfa34100acyl dehydratase (ortholog of Rv0130, which has 3-hydroxyacyl-thioester dehydratase activity. PMID:18375556)
3173nfa55760dnaBreplicative DNA helicase (putative intein at position 5911033..5912307 (found by Prof. S. Pietrokovski))
4166nfa52670dehydrogenase
5162nfa53150hypothetical protein
6160nfa48660hypothetical protein (tellurium resistance protein? antigenic protein PMID:31487535)
7160nfa3860penicillin binding protein (D-alanyl-D-alanine carboxypeptidase)
8159nfa4150Clp protease
9159nfa23120hypothetical protein
10157nfa15900nfpBcell wall channel protein (forms hetero-oligomer with NfpA; antigenic protein PMID:31487535)
11156nfa8700ABC transporter ATP-binding protein
12155nfa21360methyltransferase
13154nfa47090malate dehydrogenase
14152nfa49580hypothetical protein (adhesin like? antigenic protein PMID:31487535)
15152nfa42870hypothetical protein
16151nfa29110hypothetical protein
17151nfa36430hypothetical protein
18149nfa8810hypothetical protein
19148nfa52270hypothetical protein
20148nfa44850ftsEcell division ABC transporter ATP-binding protein
21148nfa7720ferric nocobactin-binding protein (nocobactin; upstream IdeR box-like sequence; _VIRULENCE)
22144nfa34300folDmethylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
23143nfa4390tRNA/rRNA methyltransferase
24143nfa18590hypothetical protein
25143nfa19730hypothetical protein (fosfomycin-modifying glutathione transferase?)
26143nfa23670hypothetical protein
27141nfa52820fabH3-oxoacyl-ACP synthase (typeII fatty acid synthase system)
28141nfa10210branched-chain alpha-keto acid dehydrogenase component
29140nfa5990mshDmycothiol synthase (_MYCOTHIOL; GNAT; acetyl-CoA:1D-myo-inosityl 2-(L-cysteinyl)amido-2-deoxy-alpha-D-glucopyranoside acetyltransferase)
30139nfa15250hypothetical protein (_PHAGE; putative intein at position 1682370..1683308 (found by Prof. S. Pietrokovski))
31137nfa53110cytochrome P450 monooxygenase (CYP154; F92A mutation results in altered regioselectivity (Bracco et al. PMID:24134652, PMID:25372679, PMID:33145893))
32135nfa104003-hydroxyisobutyrate dehydrogenase
33135nfa45270hypothetical protein
34135nfa36440alaSalanyl-tRNA synthetase
35135nfa6210short chain dehydrogenase
36134nfa25690hypothetical protein
37134nfa44020transcriptional regulator
38134nfa14901-acylglycerol-3-phosphate O-acyltransferase
39134nfa860hypothetical protein
40133nfa24820hypothetical protein
41133nfa43930transcriptional regulator (AraC)
42132nfa5310fadE9acyl-CoA dehydrogenase
43132nfa47390hypothetical protein (lysine decarboxylase?)
44132nfa45870hypothetical protein
45131nfa43110transcriptional regulator (TetR)
46131nfa24890transcriptional regulator
47131nfa8240hypothetical protein (type VII secretion protein EccE homolog)
48131nfa11590transcriptional regulator (MerR)
49131nfa40730proSprolyl-tRNA synthetase
50130nfa2310endoribonuclease (translation initiation inhibitor; Ininhibits protein synthesis by cleavage of mRNA)
51130nfa5470trehalose-6-phosphate synthase
52130nfa17320aroG23-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase II (2-dehydro-3-deoxyphosphoheptonate aldolase)
53130nfa32890hypothetical protein
54129nfa25390ureFurease accessory protein
55129nfa270hypothetical protein (_PHAGE)
56128nfa24030transcriptional regulator (TetR)
57128nfa16150fabDmalonyl-CoA-ACP acyltransferase (malonyl-CoA:ACP malonyltransferase; type II fatty acid synthase system)
58128nfa51470menA1,4-dihydroxy-2-naphthoate octaprenyltransferase (menaquinone/ubiquinone)
59127nfa38370glutamate transporter glutamate-binding protein
60127nfa32980transcriptional regulator (TetR)
61127nfa42200leuBisopropylmalate dehydrogenase
62126nfa9310exonuclease
63126nfa56390hypothetical protein (ErfK/YbiS/YcfS/YnhG family)
64126nfa24870transcriptional regulator
65125nfa49640two-component system response regulator
66125nfa35560hypothetical protein (NifU-like)
67125nfa51800hypothetical protein
68125nfa11750gnd6-phosphogluconate dehydrogenase
69125nfa9890acyl-CoA carboxylase alpha subunit (biotin carboxylase subunit?)
70124nfa21990short chain dehydrogenase
71124nfa6030pstBphosphate transporter ATP-binding protein
72124nfa44740transcriptional regulator
73123nfa51500hypothetical protein
74123nfa53840hypothetical protein
75123nfa37120thrSthreonyl-tRNA synthetase
76123nfa12640hypothetical protein (alkyl hydroperoxide reductase or thiol-specific antioxidant protein)
77123nfa3250ferric uptake regulator (FurA homolog)
78121nfa16240hypothetical protein
79121nfa53370thiGthiamin-thiazole moiety synthesis
80121nfa52650dihydrolipoamide dehydrogenase (_TCA)
81121nfa18700two-component system response regulator
82120nfa51030mce5EMce family protein (_VIRULENCE)
83120nfa27350phosphoglycerate mutase
84120nfa37440rlmDribosomal RNA large subunit methyltransferase (U1939)
85120nfa55000hypothetical protein
86119nfa34090phosphotransferase
87119nfa28530ptsHphosphocarrier protein (PTS HPr component)
88118nfa42800glucose 6-O-methyltransferase (PMID:17640872)
89118nfa4370mecs2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (_NON-MEVALONATE; _MEP)
90118nfa24040short chain dehydrogenase
91117nfa41270cdsAphosphatidate cytidylyltransferase
92117nfa26690hypothetical protein
93117nfa45700hypothetical protein
94117nfa1380hypothetical protein
95117nfa15880hypothetical protein (transcriptional regulator?)
96116nfa16470hypothetical protein
97116nfa6060dihydrouridine synthase
98116nfa4520hypothetical protein
99116nfa29870transporter (MFS; chloramphenicol resistance?)
100115nfa34670methylmalonyl-CoA mutase beta subunit (generate methylmalonyl-CoA from succinyl-CoA (TCA))