Top 100 Gene ranking

RankAccessIdGeneDefinition
11949nfa35380roxrifampin monooxygenase (low-level rifampin resistance _RESISTANCE; rifampin decoloration)
2217nfa15900nfpBcell wall channel protein (forms hetero-oligomer with NfpA; antigenic protein PMID:31487535)
3208nfa55760dnaBreplicative DNA helicase (putative intein at position 5911033..5912307 (found by Prof. S. Pietrokovski))
4196nfa48660hypothetical protein (tellurium resistance protein? antigenic protein PMID:31487535)
5196nfa34100acyl dehydratase (ortholog of Rv0130, which has 3-hydroxyacyl-thioester dehydratase activity. PMID:18375556)
6188nfa53110cytochrome P450 monooxygenase (CYP154; F92A mutation results in altered regioselectivity (Bracco et al. PMID:24134652, PMID:25372679, PMID:33145893))
7178nfa49580hypothetical protein (adhesin like? antigenic protein PMID:31487535)
8171nfa52670dehydrogenase
9169nfa4150Clp protease
10168nfa23120hypothetical protein
11167nfa3860penicillin binding protein (D-alanyl-D-alanine carboxypeptidase)
12165nfa8700ABC transporter ATP-binding protein
13165nfa53150hypothetical protein
14164nfa15250hypothetical protein (_PHAGE; putative intein at position 1682370..1683308 (found by Prof. S. Pietrokovski))
15163nfa21360methyltransferase
16161nfa47090malate dehydrogenase
17160nfa36430hypothetical protein
18158nfa42870hypothetical protein
19157nfa29110hypothetical protein
20157nfa8810hypothetical protein
21157nfa5990mshDmycothiol synthase (_MYCOTHIOL; GNAT; acetyl-CoA:1D-myo-inosityl 2-(L-cysteinyl)amido-2-deoxy-alpha-D-glucopyranoside acetyltransferase)
22156nfa52270hypothetical protein
23156nfa44850ftsEcell division ABC transporter ATP-binding protein
24154nfa6210short chain dehydrogenase
25153nfa18590hypothetical protein
26152nfa34300folDmethylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
27152nfa19730hypothetical protein (fosfomycin-modifying glutathione transferase?)
28152nfa4390tRNA/rRNA methyltransferase
29152nfa10210branched-chain alpha-keto acid dehydrogenase component
30152nfa7720ferric nocobactin-binding protein (nocobactin; upstream IdeR box-like sequence; _VIRULENCE)
31149nfa23670hypothetical protein
32149nfa52820fabH3-oxoacyl-ACP synthase (typeII fatty acid synthase system)
33144nfa45270hypothetical protein
34144nfa14901-acylglycerol-3-phosphate O-acyltransferase
35143nfa860hypothetical protein
36143nfa44020transcriptional regulator
37142nfa104003-hydroxyisobutyrate dehydrogenase
38141nfa36440alaSalanyl-tRNA synthetase
39141nfa5310fadE9acyl-CoA dehydrogenase
40141nfa43930transcriptional regulator (AraC)
41140nfa11590transcriptional regulator (MerR)
42140nfa24890transcriptional regulator
43140nfa24820hypothetical protein
44140nfa47390hypothetical protein (lysine decarboxylase?)
45139nfa45870hypothetical protein
46139nfa5470trehalose-6-phosphate synthase
47139nfa40730proSprolyl-tRNA synthetase
48139nfa8240hypothetical protein (type VII secretion protein EccE homolog)
49138nfa25690hypothetical protein
50137nfa32890hypothetical protein
51137nfa43110transcriptional regulator (TetR)
52137nfa2310endoribonuclease (translation initiation inhibitor; Ininhibits protein synthesis by cleavage of mRNA)
53137nfa17320aroG23-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase II (2-dehydro-3-deoxyphosphoheptonate aldolase)
54137nfa51470menA1,4-dihydroxy-2-naphthoate octaprenyltransferase (menaquinone/ubiquinone)
55136nfa32980transcriptional regulator (TetR)
56136nfa270hypothetical protein (_PHAGE)
57136nfa25390ureFurease accessory protein
58136nfa45140oxidoreductase (antigenic protein PMID:31487535)
59136nfa24030transcriptional regulator (TetR)
60136nfa16150fabDmalonyl-CoA-ACP acyltransferase (malonyl-CoA:ACP malonyltransferase; type II fatty acid synthase system)
61135nfa38370glutamate transporter glutamate-binding protein
62135nfa42200leuBisopropylmalate dehydrogenase
63134nfa9890acyl-CoA carboxylase alpha subunit (biotin carboxylase subunit?)
64134nfa35560hypothetical protein (NifU-like)
65133nfa37120thrSthreonyl-tRNA synthetase
66133nfa49640two-component system response regulator
67133nfa11750gnd6-phosphogluconate dehydrogenase
68133nfa9310exonuclease
69133nfa6030pstBphosphate transporter ATP-binding protein
70132nfa51800hypothetical protein
71132nfa56390hypothetical protein (ErfK/YbiS/YcfS/YnhG family)
72132nfa55680hypothetical protein (tellurium resistance protein? antigenic protein PMID:31487535)
73132nfa21990short chain dehydrogenase
74131nfa24870transcriptional regulator
75130nfa3250ferric uptake regulator (FurA homolog)
76130nfa44740transcriptional regulator
77130nfa18700two-component system response regulator
78130nfa12640hypothetical protein (alkyl hydroperoxide reductase or thiol-specific antioxidant protein)
79130nfa16240hypothetical protein
80130nfa37440rlmDribosomal RNA large subunit methyltransferase (U1939)
81129nfa53840hypothetical protein
82128nfa51500hypothetical protein
83128nfa51030mce5EMce family protein (_VIRULENCE)
84127nfa6060dihydrouridine synthase
85126nfa52650dihydrolipoamide dehydrogenase (_TCA)
86126nfa55000hypothetical protein
87126nfa28530ptsHphosphocarrier protein (PTS HPr component)
88126nfa43070nrdEribonucleoside-diphosphate reductase alpha subunit (putative intein at position 4465995..4467221 (found by Prof. S. Pietrokovski))
89126nfa53370thiGthiamin-thiazole moiety synthesis
90125nfa34090phosphotransferase
91125nfa24040short chain dehydrogenase
92125nfa45700hypothetical protein
93125nfa44700transcriptional regulator
94125nfa41270cdsAphosphatidate cytidylyltransferase
95125nfa4370mecs2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (_NON-MEVALONATE; _MEP)
96124nfa27350phosphoglycerate mutase
97124nfa15880hypothetical protein (transcriptional regulator?)
98124nfa4480fadE2acyl-CoA dehydrogenase
99123nfa26690hypothetical protein
100123nfa42800glucose 6-O-methyltransferase (PMID:17640872)