Top 100 Gene ranking

RankAccessIdGeneDefinition
11916nfa35380roxrifampin monooxygenase (low-level rifampin resistance _RESISTANCE; rifampin decoloration)
2188nfa34100acyl dehydratase (ortholog of Rv0130, which has 3-hydroxyacyl-thioester dehydratase activity. PMID:18375556)
3183nfa55760dnaBreplicative DNA helicase (putative intein at position 5911033..5912307 (found by Prof. S. Pietrokovski))
4176nfa48660hypothetical protein (tellurium resistance protein? antigenic protein PMID:31487535)
5167nfa52670dehydrogenase
6165nfa23120hypothetical protein
7163nfa53150hypothetical protein
8163nfa4150Clp protease
9163nfa3860penicillin binding protein (D-alanyl-D-alanine carboxypeptidase)
10162nfa15900nfpBcell wall channel protein (forms hetero-oligomer with NfpA; antigenic protein PMID:31487535)
11161nfa8700ABC transporter ATP-binding protein
12158nfa21360methyltransferase
13157nfa49580hypothetical protein (adhesin like? antigenic protein PMID:31487535)
14155nfa47090malate dehydrogenase
15155nfa36430hypothetical protein
16154nfa42870hypothetical protein
17153nfa29110hypothetical protein
18152nfa52270hypothetical protein
19152nfa8810hypothetical protein
20151nfa7720ferric nocobactin-binding protein (nocobactin; upstream IdeR box-like sequence; _VIRULENCE)
21150nfa44850ftsEcell division ABC transporter ATP-binding protein
22147nfa18590hypothetical protein
23147nfa5990mshDmycothiol synthase (_MYCOTHIOL; GNAT; acetyl-CoA:1D-myo-inosityl 2-(L-cysteinyl)amido-2-deoxy-alpha-D-glucopyranoside acetyltransferase)
24146nfa4390tRNA/rRNA methyltransferase
25146nfa10210branched-chain alpha-keto acid dehydrogenase component
26146nfa19730hypothetical protein (fosfomycin-modifying glutathione transferase?)
27146nfa34300folDmethylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
28146nfa23670hypothetical protein
29144nfa53110cytochrome P450 monooxygenase (CYP154; F92A mutation results in altered regioselectivity (Bracco et al. PMID:24134652, PMID:25372679, PMID:33145893))
30144nfa15250hypothetical protein (_PHAGE; putative intein at position 1682370..1683308 (found by Prof. S. Pietrokovski))
31143nfa52820fabH3-oxoacyl-ACP synthase (typeII fatty acid synthase system)
32139nfa6210short chain dehydrogenase
33138nfa104003-hydroxyisobutyrate dehydrogenase
34138nfa14901-acylglycerol-3-phosphate O-acyltransferase
35138nfa45270hypothetical protein
36137nfa25690hypothetical protein
37137nfa36440alaSalanyl-tRNA synthetase
38137nfa44020transcriptional regulator
39137nfa860hypothetical protein
40136nfa24820hypothetical protein
41136nfa45870hypothetical protein
42135nfa43930transcriptional regulator (AraC)
43135nfa47390hypothetical protein (lysine decarboxylase?)
44135nfa8240hypothetical protein (type VII secretion protein EccE homolog)
45135nfa5310fadE9acyl-CoA dehydrogenase
46134nfa5470trehalose-6-phosphate synthase
47134nfa11590transcriptional regulator (MerR)
48134nfa24890transcriptional regulator
49133nfa43110transcriptional regulator (TetR)
50133nfa51470menA1,4-dihydroxy-2-naphthoate octaprenyltransferase (menaquinone/ubiquinone)
51133nfa40730proSprolyl-tRNA synthetase
52132nfa17320aroG23-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase II (2-dehydro-3-deoxyphosphoheptonate aldolase)
53132nfa270hypothetical protein (_PHAGE)
54132nfa24030transcriptional regulator (TetR)
55131nfa32980transcriptional regulator (TetR)
56131nfa32890hypothetical protein
57131nfa2310endoribonuclease (translation initiation inhibitor; Ininhibits protein synthesis by cleavage of mRNA)
58130nfa16150fabDmalonyl-CoA-ACP acyltransferase (malonyl-CoA:ACP malonyltransferase; type II fatty acid synthase system)
59130nfa25390ureFurease accessory protein
60129nfa49640two-component system response regulator
61129nfa42200leuBisopropylmalate dehydrogenase
62129nfa9310exonuclease
63129nfa38370glutamate transporter glutamate-binding protein
64129nfa9890acyl-CoA carboxylase alpha subunit (biotin carboxylase subunit?)
65128nfa35560hypothetical protein (NifU-like)
66128nfa21990short chain dehydrogenase
67128nfa6030pstBphosphate transporter ATP-binding protein
68128nfa56390hypothetical protein (ErfK/YbiS/YcfS/YnhG family)
69128nfa51800hypothetical protein
70127nfa53840hypothetical protein
71127nfa37120thrSthreonyl-tRNA synthetase
72127nfa24870transcriptional regulator
73127nfa11750gnd6-phosphogluconate dehydrogenase
74126nfa3250ferric uptake regulator (FurA homolog)
75126nfa18700two-component system response regulator
76126nfa44740transcriptional regulator
77126nfa16240hypothetical protein
78126nfa12640hypothetical protein (alkyl hydroperoxide reductase or thiol-specific antioxidant protein)
79124nfa51500hypothetical protein
80124nfa37440rlmDribosomal RNA large subunit methyltransferase (U1939)
81122nfa27350phosphoglycerate mutase
82122nfa51030mce5EMce family protein (_VIRULENCE)
83122nfa28530ptsHphosphocarrier protein (PTS HPr component)
84122nfa53370thiGthiamin-thiazole moiety synthesis
85122nfa52650dihydrolipoamide dehydrogenase (_TCA)
86122nfa55000hypothetical protein
87121nfa24040short chain dehydrogenase
88121nfa6060dihydrouridine synthase
89121nfa41270cdsAphosphatidate cytidylyltransferase
90121nfa45700hypothetical protein
91121nfa34090phosphotransferase
92120nfa15880hypothetical protein (transcriptional regulator?)
93120nfa34670methylmalonyl-CoA mutase beta subunit (generate methylmalonyl-CoA from succinyl-CoA (TCA))
94119nfa26690hypothetical protein
95119nfa4370mecs2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (_NON-MEVALONATE; _MEP)
96119nfa4480fadE2acyl-CoA dehydrogenase
97119nfa42800glucose 6-O-methyltransferase (PMID:17640872)
98119nfa44700transcriptional regulator
99118nfa15740hypothetical protein
100118nfa4520hypothetical protein