Top 100 Gene ranking

RankAccessIdGeneDefinition
11922nfa35380roxrifampin monooxygenase (low-level rifampin resistance _RESISTANCE; rifampin decoloration)
2191nfa34100acyl dehydratase (ortholog of Rv0130, which has 3-hydroxyacyl-thioester dehydratase activity. PMID:18375556)
3189nfa55760dnaBreplicative DNA helicase (putative intein at position 5911033..5912307 (found by Prof. S. Pietrokovski))
4179nfa48660hypothetical protein (tellurium resistance protein? antigenic protein PMID:31487535)
5168nfa52670dehydrogenase
6166nfa23120hypothetical protein
7166nfa4150Clp protease
8165nfa15900nfpBcell wall channel protein (forms hetero-oligomer with NfpA; antigenic protein PMID:31487535)
9165nfa3860penicillin binding protein (D-alanyl-D-alanine carboxypeptidase)
10164nfa53150hypothetical protein
11163nfa8700ABC transporter ATP-binding protein
12162nfa49580hypothetical protein (adhesin like? antigenic protein PMID:31487535)
13161nfa21360methyltransferase
14158nfa36430hypothetical protein
15158nfa47090malate dehydrogenase
16157nfa42870hypothetical protein
17155nfa29110hypothetical protein
18155nfa8810hypothetical protein
19154nfa52270hypothetical protein
20153nfa44850ftsEcell division ABC transporter ATP-binding protein
21152nfa5990mshDmycothiol synthase (_MYCOTHIOL; GNAT; acetyl-CoA:1D-myo-inosityl 2-(L-cysteinyl)amido-2-deoxy-alpha-D-glucopyranoside acetyltransferase)
22152nfa7720ferric nocobactin-binding protein (nocobactin; upstream IdeR box-like sequence; _VIRULENCE)
23150nfa18590hypothetical protein
24149nfa10210branched-chain alpha-keto acid dehydrogenase component
25149nfa4390tRNA/rRNA methyltransferase
26149nfa34300folDmethylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
27149nfa15250hypothetical protein (_PHAGE; putative intein at position 1682370..1683308 (found by Prof. S. Pietrokovski))
28149nfa19730hypothetical protein (fosfomycin-modifying glutathione transferase?)
29148nfa23670hypothetical protein
30148nfa53110cytochrome P450 monooxygenase (CYP154; F92A mutation results in altered regioselectivity (Bracco et al. PMID:24134652, PMID:25372679, PMID:33145893))
31146nfa52820fabH3-oxoacyl-ACP synthase (typeII fatty acid synthase system)
32141nfa14901-acylglycerol-3-phosphate O-acyltransferase
33141nfa45270hypothetical protein
34141nfa6210short chain dehydrogenase
35140nfa104003-hydroxyisobutyrate dehydrogenase
36140nfa44020transcriptional regulator
37140nfa860hypothetical protein
38139nfa24820hypothetical protein
39139nfa36440alaSalanyl-tRNA synthetase
40138nfa45870hypothetical protein
41138nfa5310fadE9acyl-CoA dehydrogenase
42138nfa47390hypothetical protein (lysine decarboxylase?)
43138nfa43930transcriptional regulator (AraC)
44137nfa11590transcriptional regulator (MerR)
45137nfa8240hypothetical protein (type VII secretion protein EccE homolog)
46137nfa24890transcriptional regulator
47137nfa25690hypothetical protein
48136nfa40730proSprolyl-tRNA synthetase
49136nfa5470trehalose-6-phosphate synthase
50135nfa43110transcriptional regulator (TetR)
51135nfa51470menA1,4-dihydroxy-2-naphthoate octaprenyltransferase (menaquinone/ubiquinone)
52134nfa17320aroG23-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase II (2-dehydro-3-deoxyphosphoheptonate aldolase)
53134nfa24030transcriptional regulator (TetR)
54134nfa2310endoribonuclease (translation initiation inhibitor; Ininhibits protein synthesis by cleavage of mRNA)
55134nfa32890hypothetical protein
56134nfa270hypothetical protein (_PHAGE)
57133nfa16150fabDmalonyl-CoA-ACP acyltransferase (malonyl-CoA:ACP malonyltransferase; type II fatty acid synthase system)
58133nfa32980transcriptional regulator (TetR)
59133nfa25390ureFurease accessory protein
60132nfa9890acyl-CoA carboxylase alpha subunit (biotin carboxylase subunit?)
61132nfa38370glutamate transporter glutamate-binding protein
62132nfa42200leuBisopropylmalate dehydrogenase
63131nfa6030pstBphosphate transporter ATP-binding protein
64131nfa9310exonuclease
65131nfa35560hypothetical protein (NifU-like)
66131nfa49640two-component system response regulator
67130nfa21990short chain dehydrogenase
68130nfa11750gnd6-phosphogluconate dehydrogenase
69130nfa37120thrSthreonyl-tRNA synthetase
70130nfa56390hypothetical protein (ErfK/YbiS/YcfS/YnhG family)
71130nfa51800hypothetical protein
72129nfa24870transcriptional regulator
73128nfa44740transcriptional regulator
74128nfa53840hypothetical protein
75128nfa16240hypothetical protein
76128nfa3250ferric uptake regulator (FurA homolog)
77128nfa12640hypothetical protein (alkyl hydroperoxide reductase or thiol-specific antioxidant protein)
78128nfa18700two-component system response regulator
79127nfa37440rlmDribosomal RNA large subunit methyltransferase (U1939)
80126nfa51500hypothetical protein
81125nfa51030mce5EMce family protein (_VIRULENCE)
82124nfa52650dihydrolipoamide dehydrogenase (_TCA)
83124nfa53370thiGthiamin-thiazole moiety synthesis
84124nfa55000hypothetical protein
85124nfa6060dihydrouridine synthase
86124nfa28530ptsHphosphocarrier protein (PTS HPr component)
87123nfa41270cdsAphosphatidate cytidylyltransferase
88123nfa27350phosphoglycerate mutase
89123nfa24040short chain dehydrogenase
90123nfa45700hypothetical protein
91123nfa34090phosphotransferase
92122nfa44700transcriptional regulator
93122nfa4480fadE2acyl-CoA dehydrogenase
94122nfa15880hypothetical protein (transcriptional regulator?)
95122nfa4370mecs2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (_NON-MEVALONATE; _MEP)
96121nfa42800glucose 6-O-methyltransferase (PMID:17640872)
97121nfa34670methylmalonyl-CoA mutase beta subunit (generate methylmalonyl-CoA from succinyl-CoA (TCA))
98121nfa26690hypothetical protein
99120nfa4520hypothetical protein
100120nfa1380hypothetical protein