Top 100 Gene ranking

RankAccessIdGeneDefinition
11660nfa35380roxrifampin monooxygenase (low-level rifampin resistance _RESISTANCE; rifampin decoloration)
2187nfa34100acyl dehydratase (ortholog of Rv0130, which has 3-hydroxyacyl-thioester dehydratase activity. PMID:18375556)
3172nfa55760dnaBreplicative DNA helicase (putative intein at position 5911033..5912307 (found by Prof. S. Pietrokovski))
4163nfa52670dehydrogenase
5160nfa48660hypothetical protein (tellurium resistance protein? antigenic protein PMID:31487535)
6160nfa53150hypothetical protein
7158nfa23120hypothetical protein
8157nfa4150Clp protease
9156nfa15900nfpBcell wall channel protein (forms hetero-oligomer with NfpA; antigenic protein PMID:31487535)
10156nfa3860penicillin binding protein (D-alanyl-D-alanine carboxypeptidase)
11154nfa8700ABC transporter ATP-binding protein
12152nfa21360methyltransferase
13151nfa47090malate dehydrogenase
14151nfa49580hypothetical protein (adhesin like? antigenic protein PMID:31487535)
15150nfa42870hypothetical protein
16150nfa36430hypothetical protein
17147nfa29110hypothetical protein
18147nfa8810hypothetical protein
19147nfa44850ftsEcell division ABC transporter ATP-binding protein
20146nfa7720ferric nocobactin-binding protein (nocobactin; upstream IdeR box-like sequence; _VIRULENCE)
21145nfa52270hypothetical protein
22143nfa19730hypothetical protein (fosfomycin-modifying glutathione transferase?)
23142nfa34300folDmethylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
24142nfa4390tRNA/rRNA methyltransferase
25141nfa52820fabH3-oxoacyl-ACP synthase (typeII fatty acid synthase system)
26141nfa18590hypothetical protein
27140nfa23670hypothetical protein
28139nfa15250hypothetical protein (_PHAGE; putative intein at position 1682370..1683308 (found by Prof. S. Pietrokovski))
29138nfa10210branched-chain alpha-keto acid dehydrogenase component
30138nfa5990mshDmycothiol synthase (_MYCOTHIOL; GNAT; acetyl-CoA:1D-myo-inosityl 2-(L-cysteinyl)amido-2-deoxy-alpha-D-glucopyranoside acetyltransferase)
31137nfa53110cytochrome P450 monooxygenase (CYP154; F92A mutation results in altered regioselectivity (Bracco et al. PMID:24134652, PMID:25372679, PMID:33145893))
32134nfa104003-hydroxyisobutyrate dehydrogenase
33133nfa6210short chain dehydrogenase
34133nfa36440alaSalanyl-tRNA synthetase
35132nfa25690hypothetical protein
36132nfa45270hypothetical protein
37132nfa44020transcriptional regulator
38132nfa24820hypothetical protein
39131nfa860hypothetical protein
40131nfa5310fadE9acyl-CoA dehydrogenase
41131nfa45870hypothetical protein
42130nfa8240hypothetical protein (type VII secretion protein EccE homolog)
43130nfa43930transcriptional regulator (AraC)
44130nfa14901-acylglycerol-3-phosphate O-acyltransferase
45130nfa24890transcriptional regulator
46129nfa17320aroG23-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase II (2-dehydro-3-deoxyphosphoheptonate aldolase)
47129nfa47390hypothetical protein (lysine decarboxylase?)
48129nfa5470trehalose-6-phosphate synthase
49128nfa2310endoribonuclease (translation initiation inhibitor; Ininhibits protein synthesis by cleavage of mRNA)
50128nfa43110transcriptional regulator (TetR)
51128nfa40730proSprolyl-tRNA synthetase
52128nfa32890hypothetical protein
53127nfa270hypothetical protein (_PHAGE)
54127nfa11590transcriptional regulator (MerR)
55127nfa25390ureFurease accessory protein
56127nfa16150fabDmalonyl-CoA-ACP acyltransferase (malonyl-CoA:ACP malonyltransferase; type II fatty acid synthase system)
57126nfa24030transcriptional regulator (TetR)
58126nfa32980transcriptional regulator (TetR)
59126nfa38370glutamate transporter glutamate-binding protein
60125nfa51470menA1,4-dihydroxy-2-naphthoate octaprenyltransferase (menaquinone/ubiquinone)
61125nfa42200leuBisopropylmalate dehydrogenase
62125nfa24870transcriptional regulator
63124nfa49640two-component system response regulator
64124nfa35560hypothetical protein (NifU-like)
65124nfa56390hypothetical protein (ErfK/YbiS/YcfS/YnhG family)
66124nfa9310exonuclease
67123nfa11750gnd6-phosphogluconate dehydrogenase
68123nfa51800hypothetical protein
69123nfa21990short chain dehydrogenase
70122nfa51500hypothetical protein
71122nfa9890acyl-CoA carboxylase alpha subunit (biotin carboxylase subunit?)
72121nfa53840hypothetical protein
73121nfa12640hypothetical protein (alkyl hydroperoxide reductase or thiol-specific antioxidant protein)
74121nfa44740transcriptional regulator
75121nfa6030pstBphosphate transporter ATP-binding protein
76120nfa3250ferric uptake regulator (FurA homolog)
77120nfa52650dihydrolipoamide dehydrogenase (_TCA)
78120nfa16240hypothetical protein
79119nfa37120thrSthreonyl-tRNA synthetase
80119nfa28530ptsHphosphocarrier protein (PTS HPr component)
81119nfa34090phosphotransferase
82119nfa55000hypothetical protein
83119nfa18700two-component system response regulator
84118nfa53370thiGthiamin-thiazole moiety synthesis
85118nfa51030mce5EMce family protein (_VIRULENCE)
86117nfa4370mecs2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (_NON-MEVALONATE; _MEP)
87117nfa37440rlmDribosomal RNA large subunit methyltransferase (U1939)
88117nfa27350phosphoglycerate mutase
89117nfa42800glucose 6-O-methyltransferase (PMID:17640872)
90116nfa41270cdsAphosphatidate cytidylyltransferase
91116nfa1380hypothetical protein
92116nfa6060dihydrouridine synthase
93116nfa45700hypothetical protein
94115nfa4520hypothetical protein
95115nfa26690hypothetical protein
96115nfa16470hypothetical protein
97115nfa24040short chain dehydrogenase
98115nfa15880hypothetical protein (transcriptional regulator?)
99114nfa29870transporter (MFS; chloramphenicol resistance?)
100114nfa4480fadE2acyl-CoA dehydrogenase