Last modified: 2024-05-31 14:46:02 (JST) by jun@niid.go.jp

What's new (also called Change History)

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[2024-05-31] BLAST search function has been fixed.
[2023-08-25] The server has now been SSLized.
[2022-01-17] Updated all Pfam results. (Pfam 35.0/HMMER3)
[2021-11-10] BLAST search function has been fixed. Sorry for inconvenience.
[2021-06-28] Updated all Pfam results. (Pfam 34.0/HMMER3)
[2020-11-06] Protein engineering of the Nfa53110 protein (CYP154) has been reported by Bracco et al. (PMID:33145893)
[2020-08-24] Updated annotations for nfa34550-34580 according to the paper of nocardiolactone biosynthetic genes (PMID:32826316).
[2020-06-17] Updated all Pfam results. (Pfam 33.1/HMMER3) Several hypothetical genes were annotated as the results.
[2019-11-28] M. tuberculosis H37Rv data has been updated to the Mycobrowser_v3 dated 2018-06-05.
[2019-10-25] Updated all BLASTP results against the nr_v5 databese dated 2019-09-26.
[2019-10-18] Xu, S. et al. identified five gene products (Nfa45140, Nfa55680, Nfa48660, Nfa49580 and Nfa15900) of the strain IFM 10152 as antigenic proteins (PMID:31487535).
[2019-07-01] Enzyme characterizetion of the Rox protein has been reported by Abdelwahab et al. (PMID:27706151)
[2018-10-19] Updated all Pfam results. (Pfam 32.0/HMMER3) Several hypothetical genes were annotated as the results.
[2018-08-17] Updated all BLASTP results against the nr databese dated 2018-07-16.
[2017-10-11] A paper using the strain N. farcinica IFM 10152 has been published by Bernardin Souibgui et al. [PeerJ 5:e3823 (2017)]
[2017-06-02] M. tuberculosis H37Rv data has been updated to the release 26 (NC_000962.3).
[2017-04-18] Updated all BLASTP results against the nr databese dated 2017-04-02.
[2017-04-04] Updated all Pfam results. (Pfam 31.0/HMMER3) Several hypothetical genes were annotated as the results.
[2016-12-05] Updated all Pfam results. (Pfam 30.0/HMMER3) Several hypothetical genes were annotated as the results.
[2016-08-29] Crystal strucure of the Rox protein has been solved by Liu et al. (PMID:27557658)
[2016-01-15] Updated all BLAST results.
[2016-01-08] Updated all Pfam results. (Pfam 29.0/HMMER3) Several hypothetical genes were annotated as the results.
[2013-11-06] Annotated nfa44220-44280 as CRISPR-associated protein genes.
[2013-04-02] Updated all Pfam results. (Pfam 27.0/HMMER3) Several hypothetical genes were annotated as the results.
[2012-10-08] The genome data of Nocardia brasiliensis ATCC 700358 have been imported.
[2012-09-26] Updated all BLAST results.
[2012-03-13] The genome data of Nocardia cyriacigeorgica GUH-2, one of the most studied nocardial strain, have been imported.
[2012-01-19] Updated all BLAST results.
[2012-01-18] Updated all Pfam results. (Pfam 26.0/HMMER3) Many hypothetical genes were annotated as the results.
[2011-05-02] Updated all BLAST results.
[2011-04-28] Updated all Pfam results. (Pfam 25.0/HMMER3)
[2010-12-30] Nocobactin paper has been published in J. Bacteriol. vol. 193, no. 2.
[2010-04-22] Updated all Pfam results. (Pfam 24.0/HMMER3)
[2010-01-27] Our latest work has been published in J. Antibiot. vol. 63, no. 1.
[2009-11-06] Added the information about orthologs of Gordonia bronchialis DSM 43247 proteins.
[2009-11-05] Changed the annotation of nfa10360 from methylmalonyl-CoA mutase to isobutyryl-CoA mutase (icmF) according to the paper written by Cracan et al. [PubMed].
[2009-09-03] Updated all BLAST results (using blast+).
[2009-06-12] pNV128, a hygromycin-resistant version, is now available.
[2009-04-04] Added the information about orthologs of Rhodococcus erythropolis PR4 proteins.
[2009-03-27] Updated all BLAST results (using blast+).
[2009-02-03] Found five new genes (pnf1233, pnf1235, pnf1237, pnf1303 and pnf1307) by using MetaGeneAnnotator.
[2008-12-14] Updated all BLAST results.
[2008-09-12] Annotated nfa18420 as an arylamine N-acetyltransferase gene. Martins et al. cloned this gene in E. coli and functionally and structurally analyzed the purified enzyme. This is the first N. farcinica protein for which a 3D structure is reported. [PubMed]
[2008-09-09] Updated all Pfam results. (Pfam 23.0)
[2008-08-14] The release 10 data of M. tuberculosis H37Rv genome have been imported.
[2008-05-16] The release 9 data of M. tuberculosis H37Rv genome have been imported.
[2008-05-14] Updated all BLAST results.
[2008-05-10] Submitted the latest annotation to DDBJ.
[2008-04-28] Annotated nfa20040 as a channel protein as reported in Siroy et al., J. Biol. Chem. (2008) [PubMed].
[2008-04-10] Annotated nfa34100 as an acyl dehydratase gene and fixed its coordinate.
[2008-01-24] pNV118 and pNV119, high-copy-number versions, are now available.
[2007-12-20] Nucleotide sequences of pNV vectors have been updated.
[2007-11-08] The information of the Mycobacterium tuberculosis H37Rv genome (release 7) is locally available through the Genome Viewer.
[2007-09-10] Annotated nfa51180 and nfa53790 as dehydratase genes.
[2007-07-23] Found a new gene (nfa15657).
[2007-07-14] Updated all Pfam results. (Pfam 22.0)
[2007-03-29] Updated all BLAST results.
[2007-03-15] The gidB gene has been renamed to rsmG, according to Andersen and Douthwaite (J. Mol. Biol. 359:777-786, 2006).
[2007-03-08] Added the analyses results of the Inverted Repeat Finder (IRF).
[2007-02-22] The vector paper has been published in Jpn. J. Infect. Dis. vol. 60 no. 1.
[2006-12-03] Updated all Pfam results. (Pfam 21.0)
[2006-09-14] We have received the report that N. nova and N. cyriacigeorgica could be transformed with pNV18 (Drs. J. Schloendorn and B. Rittmann).
[2006-08-15] Added the information about orthologs of Rhodococcus sp. RHA1 proteins.
[2006-08-02] KEGG button has been implemented in annotation view.
[2006-07-31] pNV18 and pNV19 sequences have been deposited in the DDBJ database under accession numbers AB267085 and AB267086, respectively.
[2006-05-22] Updated all Pfam results. (Pfam 20.0)
[2006-05-09] pNV18.1 and pNV19.1 are available.
[2006-05-02] We have received reports that pNV18 and pNV19 worked in N. uniformis subsp. tsuyamanensis ATCC 21806 (taxonomically probably belongs to Actinosynnema) (Dr. David Bartley)
[2006-04-26] Updated all BLAST results.
[2006-04-11] Annotated nfa1950 as an arabinofuranosyltransferase gene.
[2006-04-01] rpoB2 paper has been published in Antimicrob. Agents Chemother. vol. 50 no. 4.
[2006-03-14] Genome viewer (gview) is now powered by Ajax.
[2006-02-19] Added the information about orthologs of Frankia sp. CcI3 proteins.
[2006-02-09] Nocardia-E. coli shuttle vectors are now available.
[2006-01-31] Updated ortholog data (E. coli, M. tuberculosis & S. cerevisiae)
[2006-01-28] Nfa53110 and Nfa33880 proteins have been confirmed experimetally their testosterone-hydroxylating acitivies by Agematu, Arisawa et al. Biosci. Biotechnol. Biochem. 70:307-311 (2006) [PubMed]
[2006-01-19] Contribution of rpoB2 to rifampin resistance has been confirmed experimentally (cloning in N. asteroides and gene knockout). Antimicrob. Agents Chemother. in press (2006)
[2006-01-04] Updated all Pfam results. (Pfam 19.0)
[2005-12-09] Added a link to GTOP database.
[2005-11-24] Updated all BLAST results.
[2005-10-13] Revised the 5'-end of nfa44030.
[2005-10-13] Found a new gene (nfa20495).
[2005-09-07] Annotated nfa1700 as a hydrolase gene.
[2005-09-07] Updated all Pfam results. (Pfam 18.0)
[2005-08-10] Genomic DNA clones are available.
[2005-08-09] Updated all BLAST results.
[2005-08-02] Annotated a putative phage protein gene, nfa505. (Thank you Prof. Sunairi)
[2005-07-01] Added RSS feeds at the rightmost position of the navigation bar.
[2005-05-11] Updated all BLAST results.
[2005-04-13] Changed the annotation of nfa17070 from asnB (asparagine synthetase gene) to ltsA (glutamine amidotransferase gene).
[2005-04-09] Updated all Pfam results. (Pfam 17.0)
[2005-03-24] Updated all BLAST results.
[2005-02-18] Updated all BLAST results.
[2005-01-09] Annotated putative mycothiol biosynthetic genes (nfa51920 (mshA), nfa47570 (mshB), nfa29340 (mshC) and nfa5990 (mshD))
[2005-01-01] Updated all BLAST results.
[2004-12-14] Added the information about tandem repeats.
[2004-11-26] Annotated nfa380 as a phage terminase small subunit gene.
[2004-11-25] Revised the 5'-end of nfa19450, and added five new putative genes (nfa2585, nfa15815, nfa19455, nfa33085 and nfa47755).
[2004-11-17] Annotated putative carotenoid biosynthetic genes (nfa7290, nfa17350, nfa17370, nfa17390, nfa17530, nfa17530, nfa34900, nfa43980 and nfa44000).
[2004-11-15] Updated all Pfam results. (Pfam 16.0)
[2004-11-07] Updated all BLAST results.
[2004-11-03] Added the information about orthologs of Streptomyces coelicolor A3(2) proteins.
[2004-11-02] Found a new gene (nfa7455).
[2004-11-01] Updated the annotation of nfa41180. (Thank you Prof. Dairi)
[2004-10-29] Added a PFGE photo to the gallery page.
[2004-10-24] Fixed a bug on "Keyword search". Now you can search the database with locus tag (e.g. nfa12340) as a keyword.
[2004-10-12] The paper was published in the journal PNAS volume 101 number 41 page 14925.
[2004-10-11] Added intein information to nrdE, dnaB and nfa15250. (Thank you Shmuel)
[2004-10-08] The genomic sequence appeared in the DDBJ database under accession numbers AP006618, AP006619 and AP006620.
[2004-10-07] Protein database is available on the BLAST search.
[2004-10-06] The complete and fully annotated genomic sequence is publicly available.
[2004-10-04] The paper is available on the PNAS early edition.
[2003-09-29] BLAST search against a draft assembly is available.