Last modified:
2024-05-31 14:46:02 (JST)
by jun@niid.go.jp
[2024-05-31]
BLAST search function has been fixed.
[2023-08-25]
The server has now been SSLized .
[2022-01-17]
Updated all Pfam results. (Pfam 35.0 /HMMER3)
[2021-11-10]
BLAST search function has been fixed. Sorry for inconvenience.
[2021-06-28]
Updated all Pfam results. (Pfam 34.0 /HMMER3)
[2020-11-06]
Protein engineering of the Nfa53110 protein (CYP154) has been reported by Bracco et al. (PMID:33145893 )
[2020-08-24]
Updated annotations for nfa34550-34580 according to the paper of nocardiolactone biosynthetic genes (PMID:32826316 ).
[2020-06-17]
Updated all Pfam results. (Pfam 33.1 /HMMER3) Several hypothetical genes were annotated as the results.
[2019-11-28]
M. tuberculosis H37Rv data has been updated to the Mycobrowser_v3 dated 2018-06-05.
[2019-10-25]
Updated all BLASTP results against the nr_v5 databese dated 2019-09-26.
[2019-10-18]
Xu, S. et al. identified five gene products (Nfa45140 , Nfa55680 , Nfa48660 , Nfa49580 and Nfa15900 ) of the strain IFM 10152 as antigenic proteins (PMID:31487535 ).
[2019-07-01]
Enzyme characterizetion of the Rox protein has been reported by Abdelwahab et al. (PMID:27706151 )
[2018-10-19]
Updated all Pfam results. (Pfam 32.0/HMMER3) Several hypothetical genes were annotated as the results.
[2018-08-17]
Updated all BLASTP results against the nr databese dated 2018-07-16.
[2017-10-11]
A paper using the strain N. farcinica IFM 10152 has been published by Bernardin Souibgui et al. [PeerJ 5:e3823 (2017) ]
[2017-06-02]
M. tuberculosis H37Rv data has been updated to the release 26 (NC_000962.3 ).
[2017-04-18]
Updated all BLASTP results against the nr databese dated 2017-04-02.
[2017-04-04]
Updated all Pfam results. (Pfam 31.0 /HMMER3) Several hypothetical genes were annotated as the results.
[2016-12-05]
Updated all Pfam results. (Pfam 30.0/HMMER3) Several hypothetical genes were annotated as the results.
[2016-08-29]
Crystal strucure of the Rox protein has been solved by Liu et al. (PMID:27557658 )
[2016-01-15]
Updated all BLAST results.
[2016-01-08]
Updated all Pfam results. (Pfam 29.0/HMMER3) Several hypothetical genes were annotated as the results.
[2013-11-06]
Annotated nfa44220-44280 as CRISPR-associated protein genes.
[2013-04-02]
Updated all Pfam results. (Pfam 27.0/HMMER3) Several hypothetical genes were annotated as the results.
[2012-10-08]
The genome data of Nocardia brasiliensis ATCC 700358 have been imported.
[2012-09-26]
Updated all BLAST results.
[2012-03-13]
The genome data of Nocardia cyriacigeorgica GUH-2, one of the most studied nocardial strain, have been imported.
[2012-01-19]
Updated all BLAST results.
[2012-01-18]
Updated all Pfam results. (Pfam 26.0/HMMER3) Many hypothetical genes were annotated as the results.
[2011-05-02]
Updated all BLAST results.
[2011-04-28]
Updated all Pfam results. (Pfam 25.0/HMMER3)
[2010-12-30]
Nocobactin paper has been published in J. Bacteriol. vol. 193, no. 2 .
[2010-04-22]
Updated all Pfam results. (Pfam 24.0/HMMER3)
[2010-01-27]
Our latest work has been published in J. Antibiot. vol. 63, no. 1 .
[2009-11-06]
Added the information about orthologs of Gordonia bronchialis DSM 43247 proteins.
[2009-11-05]
Changed the annotation of nfa10360 from methylmalonyl-CoA mutase to isobutyryl-CoA mutase (icmF ) according to the paper written by Cracan et al. [PubMed ].
[2009-09-03]
Updated all BLAST results (using blast+).
[2009-06-12]
pNV128, a hygromycin-resistant version, is now available.
[2009-04-04]
Added the information about orthologs of Rhodococcus erythropolis PR4 proteins.
[2009-03-27]
Updated all BLAST results (using blast+).
[2009-02-03]
Found five new genes (pnf1233 , pnf1235 , pnf1237 , pnf1303 and pnf1307 ) by using MetaGeneAnnotator .
[2008-12-14]
Updated all BLAST results.
[2008-09-12]
Annotated nfa18420 as an arylamine N -acetyltransferase gene. Martins et al. cloned this gene in E. coli and functionally and structurally analyzed the purified enzyme. This is the first N. farcinica protein for which a 3D structure is reported. [PubMed ]
[2008-09-09]
Updated all Pfam results. (Pfam 23.0)
[2008-08-14]
The release 10 data of M. tuberculosis H37Rv genome have been imported.
[2008-05-16]
The release 9 data of M. tuberculosis H37Rv genome have been imported.
[2008-05-14]
Updated all BLAST results.
[2008-05-10]
Submitted the latest annotation to DDBJ.
[2008-04-28]
Annotated nfa20040 as a channel protein as reported in Siroy et al. , J. Biol. Chem. (2008) [PubMed ].
[2008-04-10]
Annotated nfa34100 as an acyl dehydratase gene and fixed its coordinate.
[2008-01-24]
pNV118 and pNV119, high-copy-number versions, are now available.
[2007-12-20]
Nucleotide sequences of pNV vectors have been updated.
[2007-11-08]
The information of the Mycobacterium tuberculosis H37Rv genome (release 7 ) is locally available through the Genome Viewer .
[2007-09-10]
Annotated nfa51180 and nfa53790 as dehydratase genes.
[2007-07-23]
Found a new gene (nfa15657 ).
[2007-07-14]
Updated all Pfam results. (Pfam 22.0)
[2007-03-29]
Updated all BLAST results.
[2007-03-15]
The gidB gene has been renamed to rsmG , according to Andersen and Douthwaite (J. Mol. Biol. 359: 777-786, 2006).
[2007-03-08]
Added the analyses results of the Inverted Repeat Finder (IRF).
[2007-02-22]
The vector paper has been published in Jpn. J. Infect. Dis. vol. 60 no. 1.
[2006-12-03]
Updated all Pfam results. (Pfam 21.0)
[2006-09-14]
We have received the report that N. nova and N. cyriacigeorgica could be transformed with pNV18 (Drs. J. Schloendorn and B. Rittmann).
[2006-08-15]
Added the information about orthologs of Rhodococcus sp. RHA1 proteins.
[2006-08-02]
KEGG button has been implemented in annotation view.
[2006-07-31]
pNV18 and pNV19 sequences have been deposited in the DDBJ database under accession numbers AB267085 and AB267086, respectively.
[2006-05-22]
Updated all Pfam results. (Pfam 20.0)
[2006-05-09]
pNV18.1 and pNV19.1 are available.
[2006-05-02]
We have received reports that pNV18 and pNV19 worked in N. uniformis subsp. tsuyamanensis ATCC 21806 (taxonomically probably belongs to Actinosynnema ) (Dr. David Bartley)
[2006-04-26]
Updated all BLAST results.
[2006-04-11]
Annotated nfa1950 as an arabinofuranosyltransferase gene.
[2006-04-01]
rpoB2 paper has been published in Antimicrob. Agents Chemother. vol. 50 no. 4.
[2006-03-14]
Genome viewer (gview) is now powered by Ajax .
[2006-02-19]
Added the information about orthologs of Frankia sp. CcI3 proteins.
[2006-02-09]
Nocardia-E. coli shuttle vectors are now available.
[2006-01-31]
Updated ortholog data (E. coli , M. tuberculosis & S. cerevisiae )
[2006-01-28]
Nfa53110 and Nfa33880 proteins have been confirmed experimetally their testosterone-hydroxylating acitivies by Agematu, Arisawa et al. Biosci. Biotechnol. Biochem. 70 :307-311 (2006) [PubMed ]
[2006-01-19]
Contribution of rpoB2 to rifampin resistance has been confirmed experimentally (cloning in N. asteroides and gene knockout). Antimicrob. Agents Chemother. in press (2006)
[2006-01-04]
Updated all Pfam results. (Pfam 19.0)
[2005-12-09]
Added a link to GTOP database.
[2005-11-24]
Updated all BLAST results.
[2005-10-13]
Revised the 5'-end of nfa44030 .
[2005-10-13]
Found a new gene (nfa20495 ).
[2005-09-07]
Annotated nfa1700 as a hydrolase gene.
[2005-09-07]
Updated all Pfam results. (Pfam 18.0)
[2005-08-10]
Genomic DNA clones are available.
[2005-08-09]
Updated all BLAST results.
[2005-08-02]
Annotated a putative phage protein gene, nfa505 . (Thank you Prof. Sunairi)
[2005-07-01]
Added RSS feeds at the rightmost position of the navigation bar.
[2005-05-11]
Updated all BLAST results.
[2005-04-13]
Changed the annotation of nfa17070 from asnB (asparagine synthetase gene) to ltsA (glutamine amidotransferase gene).
[2005-04-09]
Updated all Pfam results. (Pfam 17.0)
[2005-03-24]
Updated all BLAST results.
[2005-02-18]
Updated all BLAST results.
[2005-01-09]
Annotated putative mycothiol biosynthetic genes (nfa51920 (mshA) , nfa47570 (mshB) , nfa29340 (mshC) and nfa5990 (mshD) )
[2005-01-01]
Updated all BLAST results.
[2004-12-14]
Added the information about tandem repeats .
[2004-11-26]
Annotated nfa380 as a phage terminase small subunit gene.
[2004-11-25]
Revised the 5'-end of nfa19450 , and added five new putative genes (nfa2585 , nfa15815 , nfa19455 , nfa33085 and nfa47755 ).
[2004-11-17]
Annotated putative carotenoid biosynthetic genes (nfa7290 , nfa17350 , nfa17370 , nfa17390 , nfa17530 , nfa17530 , nfa34900 , nfa43980 and nfa44000 ).
[2004-11-15]
Updated all Pfam results. (Pfam 16.0)
[2004-11-07]
Updated all BLAST results.
[2004-11-03]
Added the information about orthologs of Streptomyces coelicolor A3(2) proteins.
[2004-11-02]
Found a new gene (nfa7455 ).
[2004-11-01]
Updated the annotation of nfa41180 . (Thank you Prof. Dairi)
[2004-10-29]
Added a PFGE photo to the gallery page .
[2004-10-24]
Fixed a bug on "Keyword search". Now you can search the database with locus tag (e.g. nfa12340) as a keyword.
[2004-10-12]
The paper was published in the journal PNAS volume 101 number 41 page 14925 .
[2004-10-11]
Added intein information to nrdE , dnaB and nfa15250 . (Thank you Shmuel)
[2004-10-08]
The genomic sequence appeared in the DDBJ database under accession numbers AP006618, AP006619 and AP006620.
[2004-10-07]
Protein database is available on the BLAST search .
[2004-10-06]
The complete and fully annotated genomic sequence is publicly available.
[2004-10-04]
The paper is available on the PNAS early edition .
[2003-09-29]
BLAST search against a draft assembly is available.